Table 2.
Association of financial and home environment stressors with Breslow thickness in univariable and multivariable linear regression analysis.
| Univariable | Multivariable models1 | ||||
|---|---|---|---|---|---|
| Factor | n (%) | % change in Breslow (95% CI) | p | % change in Breslow (95% CI) | p |
| Perceived financial hardship | n = 1924 | n=1556 | |||
| 0 | 196 (10) | Reference | - | Reference | - |
| 1 | 428 (22) | 15.12 (2.92, 27.33) | 0.02 | 5.41 (−7.77, 18.59) | 0.42 |
| >1 | 1300 (68) | 16.55 (5.71, 27.39) | 0.003 | 8.95 (−2.71, 20.60) | 0.13 |
| Housing problems | n = 2005 | n = 1556 | |||
| 0 | 1511(75) | Reference | - | Reference | - |
| 1 | 211 (11) | −8.91 (−19.32, 1.51) | 0.09 | −5.97 (−17.54, 5.61) | 0.31 |
| >1 | 283 (14) | 2.20 (−6.98, 11.38) | 0.64 | −0.79 (−10.91, 9.33) | 0.88 |
| Negative life events | n = 2037 | N = 1629 | |||
| 0 | 1400 (69) | Reference | - | Reference | - |
| 1 | 438 (220 | 3.23 (−4.54, 10.99) | 0.42 | 6.49 (−2.06, 15.05) | 0.14 |
| >1 | 199(10) | −5.59 (−16.44, 5.05) | 0.30 | −4.14 (−15.85, 7.58) | 0.49 |
| Previous depression/anxiety | n = 2016 | n = 1648 | |||
| No | 1547(77) | Reference | - | Reference | - |
| Yes | 469(23) | −2.02 (−9.49, 5.44) | 0.66 | −3.30 (−11.73, 5.14) | 0.44 |
| Social support | n = 2124 | n = 1648 | |||
| Score | - | −0.05 (−1.27, 1.16) | 0.93 | 1.20 (−0.26, 2.66) | 0.12 |
| Internal HLOC | n = 2035 | n = 1604 | |||
| Low | 547 (27) | Reference | - | Reference | - |
| Moderate | 690 (34) | 3.58 (−4.41, 11.66) | 0.39 | 0.20 (−9.15, 8.74) | 0.96 |
| High | 798 (39) | 3.31 (−4.53, 11.15) | 0.41 | 1.15 (−7.51, 9.82) | 0.79 |
| Chance HLOC | n = 2014 | n = 1584 | |||
| Low | 638 (32) | Reference | - | Reference | - |
| Moderate | 640 (21) | −0.74 (−8.59, 7.12) | 0.85 | −2.86 (−11.60, 5.87) | 0.52 |
| High | 736 (37) | 4.21 (−3.38, 11.80) | 0.27 | 1.13 (−7.39, 9.66) | 0.79 |
| Powerful others HLOC | n = 2013 | n = 1591 | |||
| Low | 607 (30) | Reference | - | Reference | - |
| Moderate | 737 (37) | 4.80 (−2.88, 12.47) | 0.22 | 1.69 (−6.88, 10.26) | 0.70 |
| High | 669 (33) | 17.15 (9.19, 24.99) | <0.001 | 6.07 (−3.15, 15.27) | 0.20 |
1
Multivariable models with age, sex, site, vitamin D (adjusted for season and batch), Townsend score, BMI, smoking, alcohol intake and exercise