Table 6.
Association of financial and home environment stressors with overall survival in univariable and multivariable Cox proportional hazard analysis.
Censored | Died | Univariable | Multivariable models1 | |||
---|---|---|---|---|---|---|
Factor | (n=1607) n (%) | (n=576) n (%) | Hazard ratio (95% CI) | p | Hazard ratio (95% CI) | p |
Financial hardship | n = 1973 | n = 1556 | ||||
0 | 164 (82) | 35 (18) | 1 | - | 1 | - |
1 | 323 (72) | 123 (28) | 1.59 (1.04, 2.41) | 0.03 | 1.26 (0.82, 1.91) | 0.29 |
>1 | 976(73) | 352 (27) | 1.42 (0.97, 2.10) | 0.07 | 1.22 (0.83, 1.81) | 0.31 |
Housing problems | n = 2060 | n = 1621 | ||||
0 | 1164(75) | 390 (25) | 1 | - | 1 | - |
1 | 164 (76) | 51 (24) | 0.91 (1.00, 1.22) | 0.54 | 1.21 (0.87, 1.68) | 0.30 |
>1 | 193 (66) | 98 (34) | 1.25 (1.00, 1.56) | 0.05 | 1.09 (0.84, 1.42) | 0.52 |
Negative life events | n = 2092 | n = 1646 | ||||
0 | 1055 (72) | 392 (27) | 1 | - | 1 | - |
1 | 332(75) | 112 (25) | 0.94 (0.76, 1.16) | 0.59 | 1.00 (0.79, 1.28) | 0.97 |
>1 | 159(79) | 42 921) | 0.73 (0.53, 1.01) | 0.06 | 0.84 (0.58, 1.22) | 0.36 |
Hx depression/ anxiety | n = 2070 | n = 1629 | ||||
No | 1165 (73) | 428 (27) | 1 | - | 1 | - |
Yes | 366(77) | 111 (23) | 0.84 (0.68, 1.04) | 0.11 | 0.84 (0.65, 1.07) | 0.16 |
Norbeck social support scale | n = 2081 | n = 1633 | ||||
Score | - | - | 0.99 (0.98, 1.01) | 0.32 | 1.01 (0.99, 1.02) | 0.40 |
Internal HLOC | n = 2090 | n = 1604 | ||||
Low | 420 (75) | 143 (25) | 1 | - | 1 | - |
Middle | 525 (74) | 184 (26) | 1.08 (0.87, 1.35) | 0.48 | 1.14 (0.88, 1.48) | 033 |
High | 603(74) | 215 (26) | 1.10 (0.89, 1.36) | 0.85 | 0.99 (0.77, 1.27) | 0.92 |
Chance HLOC | n = 2068 | n = 1584 | ||||
Low | 506 (78) | 144 (22) | 1 | - | 1 | - |
Middle | 495 (75) | 163(25) | 1.06 (0.84, 1.32) | 0.63 | 0.83 (0.83, 1.42) | 0.55 |
High | 529(70) | 231 (30) | 1.30 (1.06, 1.60) | 0.01 | 1.28 (0.99, 1.65) | 0.06 |
Powerful others HLOC | n = 2069 | n = 1591 | ||||
Low | 511(82) | 109(18) | 1 | - | 1 | - |
Middle | 582 (77) | 173(23) | 1.31 (1.03, 1.66) | 0.03 | 0.94 (0.70, 1.25) | 0.66 |
High | 439 (63) | 255 (36) | 2.26 (1.81, 2.83) | <0.001 | 1.16 (0.87, 1.54) | 0.32 |
Multivariable models including Breslow thickness, site, age, sex, vitamin D (adjusted for season and batch), Townsend score, smoking, BMI, alcohol intake and exercise