Table 1.
| Effector | Type of Effector |
Expression | Cell(s) | Targeted genes |
mRNA stability and protein expression |
Ref. |
|---|---|---|---|---|---|---|
| METTL3 | Writer | Increased | bladder cancer EJ & T24 cells | Pri-miR221/222 | ↑DGCR8 mediated recognition. | (32) |
| METTL14 | Writer | Decreased | Acute kidney injury | YAP1 | ↑ stability | (33) |
| WTAP | Writer | Decreased | 3T3-L1 | Ccna2 | ↓ expression | (34) |
| VIRMA | Writer | Decreased | HeLa cells | IGFBP5 Notch1 |
↑ stability | (35) |
| FTO | Eraser | Increased | Transcription start sites | MTCH2 | ↓ expression | (36) |
| Decreased | Transcription start sites | miR-155 targeted genes | ↑ stability | (23) | ||
| ALKBH5 | Eraser | Increased | HTR-8& JEG-3 | CYR6I | ↓ expression | (37) |
| Decreased | ↑ stability | |||||
| YTHDF1 | Reader | Decreased | Porcine intramuscular preadipocytes | MTCH2 | ↓ expression | (36) |