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. Author manuscript; available in PMC: 2020 Jul 13.
Published in final edited form as: Nat Immunol. 2020 Jan 13;21(2):158–167. doi: 10.1038/s41590-019-0569-9

Figure 5: TOLLIP stabilizes STING protein in cells.

Figure 5:

(A) Immunoblot analysis of STING protein in Tollip+/+ and Tollip−/− MEFs treated with cycloheximide (CHX). IkBa is a control protein with short half-life that is unaffected by TOLLIP. Densitometry quantitation of protein bands are showing on the right.

(B) Immunoblot analysis of STING protein in Tollip+/+ and Tollip−/− MEFs treated with cycloheximide (CHX) alone or in combination of proteasome inhibitor BTZ or lysosome inhibitor BafA.

Data are representative of at least two independent experiments.