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. Author manuscript; available in PMC: 2021 Feb 1.
Published in final edited form as: Behav Res Ther. 2019 Oct 31;125:103507. doi: 10.1016/j.brat.2019.103507

Table 2.

MASQ Subscales Predicting Treatment Outcome

Controlling for treatment condition Time to remission within 1 year Time to recovery within 3 years
β p value HR NNT β p value HR NNT
Only MASQ subscale
 Distress −.33 <.001 0.72 6.13 −.33 <.001 0.72 6.07
 Anhedonia −.23 <.001 0.79 8.68 −.20 <.001 0.82 10.09
 Somatic −.20 .002 0.82 10.12 −.16 .008 0.86 12.77
Controlling for baseline HDRS
 Distress −.30 <.001 0.74 6.65 −.32 <.001 0.73 6.36
 Anhedonia −.20 <.001 0.81 10.00 −.17 .002 0.84 11.66
 Somatic −.15 .034 0.86 13.70 −.11 .086 0.89 17.78
Controlling for other MASQ subscales
 Distress (cont. for anhedonia) −.28 <.001 0.75 7.15 −.30 <.001 0.73 6.16
 Anhedonia (cont. for distress) −.09 .163 0.91 21.68 −.05 .392 0.95 37.39
Additional controls
 Distress (cont. for baseline HDRS, MASQ anhedonia, and MASQ somatic) −.23 .002 0.79 8.59 −.29 <.001 0.75 6.99
 Anhedonia (cont. for baseline HDRS, MASQ distress, and MASQ somatic) −.10 .149 0.91 20.46 −.05 .434 0.95 39.73
Interacting with treatment Time to remission within 1 year Time to recovery within 3 years
Only MASQ subscale β p value HR NNTa β p value HR NNTa
 Distress .26 .032 1.29 −7.84 .29 .014 1.33 −7.04
 Anhedonia .24 .036 1.27 −8.32 .30 .007 1.34 −6.79
 Somatic .04 .757 1.04 −52.28 .15 .211 1.16 −13.64
Controlling for baseline HDRS
 Distress .26 .043 1.29 −7.86 .24 .048 1.27 −8.32
 Anhedonia .24 .041 1.27 −8.37 .27 .017 1.31 −7.36
 Somatic −.01 .969 0.99 369.37 .06 .671 1.06 −36.15
Controlling for other MASQ subscales
 Distress (cont. for anhedonia) .19 .160 1.21 −10.49 .19 .153 1.21 −10.46
 Anhedonia (cont. for distress) .13 .310 1.14 −14.98 .19 .134 1.21 −10.60
Additional controls
 Distress (cont. for baseline HDRS, MASQ anhedonia, and MASQ somatic) .21 .185 1.23 −9.72 .13 .405 1.13 −15.94
 Anhedonia (cont. for baseline HDRS, MASQ distress, and MASQ somatic) .14 .313 1.15 −14.54 .20 .120 1.23 −9.83

Note. MASQ = Mood and Anxiety Symptom Questionnaire. HDRS = Hamilton Depression Rating Scale. β = Standardized regression coefficient; HR = Hazard ratio; NNT = Number needed to treat.

a

NNT values that are negative are considered Numbers Needed to Harm (NNH). NNT/NNH values were included for the interaction analyses to illustrate effect sizes, but the direction of these analyses are clarified in the text and in Figures 1–4.