Fig. 3.

Global superposition of whole pentameric models of unliganded and propylammonium-bound ELIC. (A) View parallel to the plane of the membrane. (B) View perpendicular to the plane of the membrane, from the extracellular side. For clarity, only one subunit is displayed in cartoon representation with its corresponding orthosteric-site–bound propylammonium molecule shown in van der Walls representation (cyan). All other chains are displayed in lines representation. The color code is the same for both panels. Molecular images were prepared with VMD (37). NDs: nanodiscs.