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Antitumor activity of AuMesoIX and biodistribution in mice. Tumor volume and body weight of nude mice bearing (A) A2780 or (B) HCT116 xenografts following i.v. injection of AuMesoIX (2 mg/kg) or solvent control twice per week. Data are represented as means ± SEM (n = 5; Student’s t test; *P < 0.05, compared with vehicle control group). (C) Biodistribution of gold content in liver, kidney, and urine of BALB/C mice following i.v. injection of a single dose of AuMesoIX (2 mg/kg; n = 3).
