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. 2020 Jan 21;15:363–386. doi: 10.2147/IJN.S234573

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© 2020 Derakhshankhah et al.

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Optical microscopy images demonstrating U251 cells treated with (A) 0 mg/mL of drug delivery system (DDS), (B) 0.05 mg/mL of temozolomide (TMZ) containing mordenite zeolites (MOR) (TMZ_0.026-MOR) and (C) 0.75 mg/mL of TMZ_0.026-MOR under 100x magnification and found that above 0.75 mg mL1 there is high rate of cell dead, probably because from this concentration the cells are completely coated by the zeolite, which compromise the cell-nutrient exchange with the culture media. Reprinted with permission from Ref [134] Copyright (2011), ROYAL SOCIETY OF CHEMISTRY.