Table 1. Immunohistochemical markers used in the diagnosis and subclassification of specific tumor types.

Tumor type	Immunohistochemical markers
Meningioma	Cytokeratin and E-cadherin
Glial tumor	GFAP and Olig2
Primary intracranial histiocytic sarcoma	CD204, HLA-DR, and Iba1
Choroid plexus tumor	Cytokeratin and E-cadherin
Ependymal tumor	GFAP
Intracranial lymphoma	CD3 and CD20
Embryonal tumor	β IIItubulin, doublecortin, GFAP, nestin, and synaptophysin

GFAP, glial fibrillary acidic protein; Iba1, ionized calcium-binding adapter molecule 1; Olig2, oligodendrocyte lineage transcription factor 2. Primary antibodies: β IIItubulin (clone 5G8; Promega Corp., Madison, WI, USA), CD3 (polyclonal antibody (pAb); Dako, Tokyo, Japan), CD20 (pAb; Biocare Medical, Concord, CA, USA), CD204 (clone SRA-C6; Trans Genic, Kobe, Japan), cytokeratin (clone AE1/AE3; Dako), doublecortin (pAB; Santa Cruz Biotechnology, Santa Cruz, CA, USA), E-cadherin (clone 36/E-Cadherin; BD Biosciences, San Jose, CA, USA), GFAP (pAB; Dako), HLA-DR (clone TAL 1B5; Santa Cruz Biotechnology), Iba1 (pAb; Wako, Osaka, Japan), nestin (pAB; Immuno-Biological Laboratories, Fujioka, Japan), Olig2 (pAB; Millipore, Billerica, MA, USA), and synaptophysin (clone DAK-SYNAP; Dako).