Table 1. Induction time, anesthesia duration and number of additional anesthetic injections after administration of a mixture of medetomidine, midazolam and butorphanol (MMB) by s.c. or i.p. injection, or of pentobarbital by i.p. injection in rats.
| Anesthesia | Route | N | Age (week) |
Body weight (g) |
Induction time (min) |
Anesthesia duration (min) |
Times of additional anesthetic injections (number of rats) |
|||
|---|---|---|---|---|---|---|---|---|---|---|
| Mean ± SD | Mean ± SD | Mean ± SD | Shortest | Longest | 1 | 2 | ||||
| MMB | i.p. | 7 | 8 | 349.2 ± 13.7 | 13.6 ± 3.8 | 69.3 ± 14.0 | 45 | 80 | 4 | 1 |
| MMB | s.c. | 7 | 8 | 367.8 ± 30.9 | 5.0 ± 0.0# | 135.7 ± 21.7* | 105 | 160 | 0 | 0 |
| Pentobarbital | i.p. | 14 | 10 | 423.2 ± 31.4 | 10.0 ± 3.4* | 37.9 ± 18.7* | 10 | 75 | 3 | 2 |
Data represent the means ± SD. N: number of rats. #P<0.05 and *P<0.05 as compared to the MMB group administered MMB by i.p. injection (Welch’s t-test and Student’s t-test, respectively).