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Gene expression angiogenic markers relative to 18S as compared with control at 24 h (A) and 72 h (B). Gene expression antioxidant enzymes relative to 18S compared with control at 24 h (C) and 72 h (D). ***p < 0.001, **p < 0.01, *p < 0.05 indicate statistical significance, n = 4 per group. CONTROL, endothelial cell basal medium supplemented with 2% FBS on TCP; VEGF-A, vascular endothelia growth factor A; HIF-1α, hypoxia-inducible growth factor-1α; Ang-1, angiopoietin-1; Nes-2, nesprin-2.
