Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Dec 10;295(4):1077–1090. doi: 10.1074/jbc.RA119.011424

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

PMC Copyright notice

Figure 5. — The C terminus of Nav1.9 modulates voltage-dependence of steady-state fast-inactivation but not activation. Boltzmann fits of voltage dependence of activation (A) and steady-state fast inactivation (B) for WT Nav1.9 and Nav1.7 channels and their chimeras. C, comparison of midpoint voltage of activation (V_½Act) among all tested channels showing no difference in chimeric channels Nav1.9-Ct_Nav1.7 (n = 8), Nav1.9-Ct49aa_Nav1.7 (n = 7), and Nav1.7-Ct49aaNav1.9 (n = 10), compared with parent channels Nav1.9 (n = 4) and Nav1.7 (n = 10). D, comparison of midpoint voltage of fast inactivation (V_½Inact) among all tested channels (Nav1.9-Ct_Nav1.7 (n = 8); Nav1.9-Ct49aa_Nav1.7 (n = 7); Nav1.7-Ct49aaNav1.9 (n = 10); Nav1.9 (n = 4); Nav1.7 (n = 10)). Error bars, S.E. Statistical significance is indicated by asterisks: *, p < 0.05; **, p < 0.01; ***, p < 0.001, by one-way ANOVA followed by Tukey's multiple-comparison test. ns, not significant.