Table 1.
Demographic and clinical characteristics of low fermentable oligo-, di-, mono-saccharides and polyols treated IBS with diarrhoea patients, in relation to sucrase-isomaltase genotype
| Characteristic | Non-carriers n=23 |
Carriers n=23 |
| Average age (years) | 41.22±13.55 | 43.39±16.00 |
| Sex (female/male) | 14/9 | 17/6 |
| Race (white/other) | 19/4 | 17/6 |
| Average body mass index (kg/m2) | 26.28±5.72 | 28.38±6.71 |
| Abdominal pain (average score, baseline) | 5.03±1.43 | 5.27±1.61 |
| Bloating (average score, baseline) | 4.77±1.86 | 4.84±1.89 |
| Urgency score (baseline) | 5.02±1.79 | 4.90±2.18 |
| Stool frequency (average score at baseline) | 3.41±1.38 | 3.60±2.03 |
| Bristol Stool Form (average, baseline) | 5.15±0.51 | 5.29±0.71 |
| Rare hypomorphic variants (Arg774Gly; Tyr975His; Glu1414Lys) | 0 | 3 |
| Common hypomorphic variant (Val15Phe) | 0 | 20 |