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. 2019 Mar 29;69(2):343–354. doi: 10.1136/gutjnl-2018-317725

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© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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CR-T3-SEQ13 vaccination could eradicate HBsAg and HBV DNA in hydrodynamic injection-based HBV carrier mice. A total of five doses of CR-T3-SEQ13 were injected at week 0, 2, 3, 4 and 5, respectively. (A) Dynamics of HBsAg level and (B) kinetics of anti-HBs antibody level in HDI-HBV carrier mice (genotype A, n=5). The data represent mean±SEM. HBsAg, hepatitis B virus surface antigen.