Figure 4. Radiosensitivity of Fanconi anemia cell lines is mitigated by JP4-039, but not by necrostatin-1 or baicalein. Mitigation by JP4-039 of radiation damage was detected in 129/Sv, Fanca−/−, and Fancd2−/− bone marrow stromal cells (A). In contrast, necrostatin-1 (B) or baicalein (C) mitigated irradiation damage in the 129/Sv cell line, but not the Fanca−/− or the Fancd2−/− cell lines.
