Table I. Radioprotection of Fanconi anemia bone marrow stromal cell lines by small molecule drugs JP4-039, baicalein, and necrostatin-1. 129/Sv control, Fanca−/− and Fancd2−/− bone marrow stromal cell lines were used in irradiation survival curves. JP4-039, baicalein (10 μM) and necrostatin-1 (10 μM) were added 1 h before irradiation, and cells were then kept in culture for 7 days. The cells were stained with crystal violet and colonies greater than 50 cells counted. The data were analyzed using single-hit, multi-target or linear quadratic models. Significant p-values are shown.

*For D0 vs. Control.