Figure 3. Significant mitigation of 9.25 Gy total body irradiation (TBI) delivered to C57BL/6 female mice by gavage of Lactobacillus reuteriinterleukin- 22-green fluorescent protein fusion protein (IL-22-GFP+) (109 bacteria in 100 μl saline) administered at 24, 48, or 72 h after TBI (n=12 animals per group). Compared to control irradiated mice, mice gavaged with Lactobacillus-IL-12-GFP at 24, 48 or 72 h after irradiation had increased survival (p=0.0001, 0.0047 and 0.0448, respectively.
