Table 5.
Effect of Ficus deltoidea (FD) on serum lipid profile
(Mean values and standard deviations; n 7)
| Total cholesterol (mg/dl)§ | TAG (mg/dl)§ | HDL-cholesterol (mg/dl)§ | LDL-cholesterol (mg/dl)§ | |||||
|---|---|---|---|---|---|---|---|---|
| Groups‡ | Mean | sd | Mean | sd | Mean | sd | Mean | sd |
| Normal control | 62·9 | 6·34 | 51·0 | 8·96 | 28·5 | 3·80 | 19·3 | 2·40 |
| Diabetic control | 89·5* | 6·15 | 87·5* | 5·79 | 17·4* | 3·3 | 42·2* | 7·89 |
| MET, 150 mg/kg | 59·4† | 5·19 | 57·8† | 10·47 | 29·4† | 2·66 | 20·8† | 2·87 |
| FD, 125 mg/kg | 74·3*† | 5·26 | 82·1* | 10·30 | 25·0† | 2·36 | 32·3*† | 4·81 |
| FD, 250 mg/kg | 72·6† | 9·45 | 86·3* | 4·64 | 25·5† | 4·70 | 32·5*† | 1·75 |
| FD, 500 mg/kg | 69·9† | 7·50 | 87·1* | 6·28 | 30·4† | 2·57 | 32·3*† | 1·94 |
MET, metformin.
* Mean value was statistically significantly different from that of the normal control group (P ≤ 0·05).
† Mean value was statistically significantly different from that of the diabetic control group (P ≤ 0·05).
‡ Adult male Wistar rats received either distilled water (normal control) or streptozotocin (45 mg/kg) in citrate buffer (diabetic control) by intraperitoneal injection. Diabetic rats received FD (125, 250 or 500 mg/kg, orally), MET (150 mg/kg, orally) for 4 weeks, 48 h after induction of diabetes.
§ To convert cholesterol in mg/dl to mmol/l, multiply by 0·0259. To convert TAG in mg/dl to mmol/l, multiply by 0·0113.