Table 1. The inhibitory activity of compounds 2–11 with Ldt_Mt2.

	Compound	IC50 (μM, mean ± SD)
		0 min a	10 min	60 min
2	Iodoacetamide	129 ± 14	32.5 ± 1.4	10.1 ± 0.7
3	Maleimide	158 ± 9	48.3 ± 3.6	18.6 ± 0.7
4	Ebselen	0.36 ± 0.02	0.159 ± 0.077	0.143 ± 0.014
5	PhSeBr	11.8 ± 1.3	5.05 ± 0.35	2.02 ± 0.61
6	PhSeCl	62.8 ± 2.2	24.6 ± 0.9	20.0 ± 1.2
7	PhSe(O)OH	309 ± 7	136 ± 17	93.2 ± 9.3
8	Thiram	7.01 ± 0.29	2.93 ± 0.11	0.780 ± 0.029
9	Aldrithiol	22.1 ± 0.7	5.35 ± 0.21	1.61 ± 0.03
10	PX-12	27.2 ± 0.5	9.56 ± 0.25	2.48 ± 0.10
11	Faropenem	1.69 ± 0.17	1.00 ± 0.04	0.686 ± 0.069

^aThe impact of inhibitors on Ldt_Mt2 was tested without pre-incubation, or with 10 min or 60 min pre-incubation prior to addition of fluorogenic probe 1.