Table 2.
Results of clinical ophthalmoscopic exams.
| Cat breeda | Age (years) | Sex | rdAc genotypeb | Clinical diagnosis | Stage of disease | Examination performed |
|---|---|---|---|---|---|---|
| Balinese | 5 | M | Affected | Affected | Stage 2 | Ophthalmoscopic |
| Colorpoint shorthair | 11 | F | Affected | Affected | Stage 3+ | Ophthalmoscopic |
| Oriental shorthair | 3 | F | Affected | Affected | Stage 3+ | Ophthalmoscopic |
| Oriental shorthair | 1 | M | Affected | Affected | Stage 2 | Ophthalmoscopic |
| Siamese | 3.5 | F | Affected | Affected | Stage 2 | Ophthalmoscopic |
| Siamese | 1.5 | M (N) | Affected | Affected | Stage 1 | Ophthalmoscopic, ERG |
| Siamese | 8 | F | Affected | Affected | Stage 4 | Ophthalmoscopic |
| Oriental shorthair | 8 months | F | Carrier | Unaffected | ||
| Oriental shorthair | 2 | F | Carrier | Unaffected | ||
| Oriental shorthair | 2 | F | Unaffected | Unaffected | ||
| Oriental shorthair | 10.5 | F | Carrier | Unaffected | ||
| Oriental shorthair | 3 | F | Carrier | Unaffected | ||
| Oriental shorthair | 1 | F | Carrier | Unaffected | ||
| Oriental shorthair | 6.5 | M | Carrier | Unaffected | ||
| Oriental shorthair | 4 | F | Carrier | Unaffected | ||
| Oriental shorthair | 1 | M | Carrier | Unaffected | ||
| Siamese | 18 | F | Carrier | Unaffected | ||
| Siamese | 1.5 | F | Carrier | Unaffected | ||
| Siamese (A) | 3.5 | F | Unaffected | Unaffected | ||
| Siamese (A) | 5 | F | Unaffected | Unaffected | ||
| Siamese (classic wedge) | 9 | F (S) | Unaffected | Unaffected | ||
| Siamese (wedge:traditional) | 18 | M (N) | Unaffected | Unaffected | ||
| Siamese | 8 | M (N) | Carrier | Unaffected | ||
| Siamese | 5.5 | M (N) | Unaffected | Unaffected | ||
| Siamese | 13 | M (N) | Unaffected | Unaffected | ||
| Siamese | 6 | M | Unaffected | Unaffected | ||
| Thaic | 1 | M | Unaffected | Unaffected | Ophthalmoscopic, ERG |
a
(A) refers to the rounder head style Siamese known as the ‘applehead’ – see text in results for detailed description; cats not so designated are wedge or modified wedge style head.
b
Affected: homozygous for the rdAc defining SNP, CEP290 −/−; Carrier; CEP290 +/−; Unaffected: CEP290 +/+.
c
The Thai breed is a recently recognized breed of the International Cat Association, representing recent imports from Thailand which exhibit features of the rounder-headed old-style Siamese.