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. 2019 Sep 16;37(1):183–194. doi: 10.1093/molbev/msz213

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© The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Fig. 4. — Genome-wide measures of genetic diversity and genetic load in the Dryas monkey. (A) Average number of heterozygous sites per 1,000 base pairs. (B) Fraction of the genome in runs of homozygosity (ROH) >100 kb (open bars) and fraction of the genome in ROH >2.5 Mb (solid bars). (C) Ratio of missense to synonymous mutations, excluding all missense mutations within genes containing one or more LOF mutations. (D) Ratio of LOF to synonymous mutations, counting genes with more than one LOF mutation only once.