Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Sep 20;37(1):240–259. doi: 10.1093/molbev/msz212

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 1. — Comparative transcriptomics across species, organs, and developmental stages. (A) Experimental design. The developmental stages selected for mouse, rat, and chicken are marked on a horizontal axis. Organs sampled for each species and developmental stage are shown below. Abbreviations: br, brain; kd, kidney; lv, liver; ts, testes. (B) First factorial map of a principal component analysis, performed on log2-transformed TPM values, for 10,363 protein-coding genes with orthologs in mouse, rat, and chicken. Colors represent different organs and developmental stages, point shapes represent different species. (C) Hierarchical clustering, performed on a distance matrix derived from Spearman correlations between pairs of samples, for 10,363 protein-coding genes with orthologs in mouse, rat, and chicken. Organ and developmental stages are color-coded, shown below the heatmap. Species of origin is color-coded, shown on the right. Sample clustering is shown on the left.