Study | No. of participants + stages | Timing of interim PET scan | Unadjusted results for interim PET scan |
Casasnovas 2019 | Standard arm N = 413 |
PET2 |
PET2 results (N = 398) Intention‐to‐treat analysis 5‐year OS for entire arm = 95·2% (95% CI 91·1 to 97·4), 13 events Per‐procotol analysis N = 372 participants 5‐year OS for entire arm = 95.6% (95% CI 91.2 to 97.8), 10 events Comment: Separate results for PET2‐negative and PET2‐positive participants in the standard arm were not reported for this outcome. |
Gallamini 2014 | 260 (stages IIA ‐ IVB) | PET2 | PET‐negative N = 215, 2 deaths, 3‐year OS = 99% PET‐positive N = 45, 6 deaths, 3‐year OS = 87% Comment: Logrank test for difference between groups was not reported and could not be obtained. |
Hutchings 2006 | 77 (all stages) | PET2 and PET4 |
PET2 results (N = 77) PET‐negative N = 61, no deaths PET‐positive N = 16, 2 deaths Logrank test for difference between groups: P < .01 PET4 results (N = 64) PET‐negative N = 51, no deaths PET‐positive N = 13, 2 deaths Comment: Logrank test for difference between groups after PET4 was not reported and could not be obtained. |