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. 2020 Jan 13;2020(1):CD012643. doi: 10.1002/14651858.CD012643.pub3
Study No. of participants + stages Timing of interim PET scan Unadjusted results for interim PET scan
Casasnovas 2019 Standard arm
N = 413
PET2 PET2 results (N = 398)
Intention‐to‐treat analysis
5‐year OS for entire arm = 95·2% (95% CI 91·1 to 97·4), 13 events
Per‐procotol analysis
N = 372 participants
5‐year OS for entire arm = 95.6% (95% CI 91.2 to 97.8), 10 events
Comment: Separate results for PET2‐negative and PET2‐positive participants in the standard arm were not reported for this outcome.
Gallamini 2014 260 (stages IIA ‐ IVB) PET2 PET‐negative N = 215, 2 deaths, 3‐year OS = 99%
PET‐positive N = 45, 6 deaths, 3‐year OS = 87%
Comment: Logrank test for difference between groups was not reported and could not be obtained.
Hutchings 2006 77 (all stages) PET2 and PET4 PET2 results (N = 77)
PET‐negative N = 61, no deaths
PET‐positive N = 16, 2 deaths
Logrank test for difference between groups: P < .01
PET4 results (N = 64)
PET‐negative N = 51, no deaths
PET‐positive N = 13, 2 deaths
Comment: Logrank test for difference between groups after PET4 was not reported and could not be obtained.