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. Author manuscript; available in PMC: 2020 Jan 27.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2016 May 6;25(7):1144–1150. doi: 10.1158/1055-9965.EPI-15-0894

Table 3.

Top 10 autosomal SNPs associated with risk of progression in the whole NMIBC series using multivariable Cox regression additive model

Gene SNP HR P MAF
CD3G rs3212262 2.70 1.5 × 10−5 0.09
HLA-B rs9266462 2.67 0.0026 0.06
CCL-2 rs929259 0.52 0.0081 0.37
FAS rs1571014 1.73 0.0089 0.36
PPARG rs7626560 1.85 0.0015 0.19
CXCR4 rs778192 0.55 0.0017 0.38
SOCS5 rs973491 2.11 0.0025 0.07
CXCR4 rs16834018 2.10 0.0035 0.08
CD8B1 rs13024609 1.70 0.0044 0.20
IL6 rs2069827 2.00 0.0053 0.06

NOTE: Analyses were adjusted for geographical area, age, multiplicity, tumor stage and grade, number of recurrences, and treatment (see Supplementary Table S2).