#	Searches	Results
1	(vaccin* and (uptake or coverage)).ti.	2874
2	(vaccin* adj (uptake or coverage)).ab.	7778
3	or/1‐2	8995
4	vaccination/	141,285
5	immunization/	101,664
6	mass immunization/	3442
7	or/4‐6	222,281
8	3 or 7	224,178
9	adolescent/	1,421,541
10	juvenile/	62,746
11	(adolescent? or youth? or young adult? or teenager? or teen? or juvenile?).ti,ab.	450,617
12	or/9‐11	1,599,735
13	8 and 12	19,041
14	Randomized Controlled Trial/	479,705
15	Controlled Clinical Trial/	475,294
16	Quasi Experimental Study/	4422
17	Pretest Posttest Control Group Design/	353
18	Time Series Analysis/	24,354
19	Experimental Design/	25,555
20	Multicenter Study/	164,862
21	(randomis* or randomiz* or randomly).ti,ab.	964,283
22	groups.ab.	2,227,946
23	(trial or intervention? or effect? or impact? or multicenter or multi center or multicentre or multi centre).ti.	2,390,553
24	(controlled or control group? or (before adj5 after) or (pre adj5 post) or ((pretest or pre test) and (posttest or post test)) or quasiexperiment* or quasi experiment* or evaluat* or time series or time point? or repeated measur*).ti,ab.	5,069,452
25	or/14‐24	8,222,057
26	exp animals/ or exp invertebrate/ or animal experiment/ or animal model/ or animal tissue/ or animal cell/ or nonhuman/	24,477,256
27	human/ or normal human/ or human cell/	18,584,467
28	26 and 27	18,537,629
29	26 not 28	5,939,627
30	(systematic review or literature review).ti.	108,093
31	"cochrane database of systematic reviews".jn.	5634
32	or/29‐31	6,052,569
33	25 not 32	6,461,120
34	13 and 33	7340
35	limit 34 to embase	1961
36	limit 34 to embase status	651
37	35 or 36	2134