Winer 2016.

Methods	Cluster‐randomised trial in the USA
Participants	Participants: parents Number per group: 43 parents in intervention group and 54 parents in control group Total number enrolled: 97 parents Study population: mother or female legal guardian of a girl aged 9–12 years enrolled in the Hopi Tribe
Interventions	Intervention: educational presentations on HPV Description: PowerPoint presentation with information on HPV prevalence and transmission, HPV vaccine recommendations, dosage schedule, and vaccine efficacy and safety. An educational brochure with similar content was also created to accompany the presentation. Parents attended mother–daughter dinners featuring educational presentations for mothers on HPV. Educational PowerPoint presentations provided information on HPV prevalence and transmission, HPV vaccine recommendations, dosage schedule, vaccine efficacy, and vaccine safety. An educational brochure with similar content was created to accompany the presentation. Duration: 30–40 minutes Comparison: no education on HPV Description of comparison: parents attended mother–daughter dinners featuring educational presentations for mothers on juvenile diabetes. Educational PowerPoint presentations focused on risk factors for type 2 juvenile diabetes, healthy nutrition, physical activity, and what parents could do to prevent or manage diabetes for their children. Vaccine target: HPV vaccine Disease targeted: cervical cancer Number of doses: not specified
Outcomes	HPV vaccine uptake
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Study randomly assigned 2 clusters to the intervention group and 2 to the control group.
Allocation concealment (selection bias)	Unclear risk	No description.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	The outcome is an objective measure.
Blinding of outcome assessment (detection bias) All outcomes	Low risk	The outcome is an objective measure.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No attrition bias.
Selective reporting (reporting bias)	Unclear risk	No description.
Other bias	Low risk	No evidence of other biases.

CDC: Centers for Disease Control and Prevention; CHIP: Children's Health Insurance Program; EHR: electronic health record; HIT: health information technology; HPV: human papillomavirus; MCV4: meningococcal conjugate vaccine; MOC: maintenance of certification; PBRN: practice‐based research network; RQ: rhetorical questions; Tdap: tetanus–diphtheria–acellular–pertussis.