Comparison 1. G‐CSF versus placebo or no treatment in women undergoing assisted reproduction.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1.1 Ongoing pregnancy rate	1		Risk Ratio (M‐H, Random, 95% CI)	Subtotals only
1.1.1 Unselected IVF population	1	150	Risk Ratio (M‐H, Random, 95% CI)	1.62 [0.86, 3.08]
1.2 Miscarriage rate	2	291	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.40 [0.09, 1.77]
1.2.1 Unselected IVF population	2	291	Peto Odds Ratio (Peto, Fixed, 95% CI)	0.40 [0.09, 1.77]
1.3 Clinical pregnancy rate	12	1050	Risk Ratio (M‐H, Fixed, 95% CI)	1.65 [1.32, 2.06]
1.3.1 Unselected IVF population	2	291	Risk Ratio (M‐H, Fixed, 95% CI)	1.12 [0.75, 1.68]
1.3.2 2 or more IVF failures	6	553	Risk Ratio (M‐H, Fixed, 95% CI)	2.10 [1.53, 2.89]
1.3.3 Women with thin endometrium	4	206	Risk Ratio (M‐H, Fixed, 95% CI)	1.58 [0.95, 2.63]
1.4 Adverse events	4	410	Peto Odds Ratio (Peto, Fixed, 95% CI)	Not estimable
1.4.1 Unselected IVF population	1	141	Peto Odds Ratio (Peto, Fixed, 95% CI)	Not estimable
1.4.2 2 or more IVF failures	3	269	Peto Odds Ratio (Peto, Fixed, 95% CI)	Not estimable
1.5 Ectopic pregnancy rate	1		Peto Odds Ratio (Peto, Fixed, 95% CI)	Subtotals only
1.5.1 Unselected IVF population	0	0	Peto Odds Ratio (Peto, Fixed, 95% CI)	Not estimable
1.5.2 2 or more IVF failures	1	112	Peto Odds Ratio (Peto, Fixed, 95% CI)	1.97 [0.20, 19.35]