Singh 2015.

Study characteristics
Methods	RCT Single centre India
Participants	Women undergoing fresh IVF cycle with thin endometrium. Previous traditional methods of treating thin endometrium have been unsuccessful (oestradiol and sildenafil).
Interventions	Intervention group (N = 24): intrauterine infusion of G‐CSF (300 μg/mL) on day of trigger, repeated after 48 hours if endometrial thickness was < 7 mm Control group (N = 24): saline intrauterine infusion on day of trigger
Outcomes	Implantation and pregnancy rates, endometrial thickness
Notes	Study was published as conference abstract only. Partial response to queries on data was received from authors. No clinical trial registration number available.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Quote: “Patient were randomly divided into two groups using computer generated list”
Allocation concealment (selection bias)	Unclear risk	No information on allocation concealment
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Placebo (intrauterine saline infusion) was used in the control group. No specific information as to whether participants/clinician/embryologist were blinded
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Does not specify if outcome assessors were blinded. However, absence of blinding is unlikely to have influenced the findings for our primary and secondary outcomes, hence categorised as low risk for detection bias.
Incomplete outcome data (attrition bias) All outcomes	Low risk	No information was available on dropouts, however all randomised women were included in final analysis.
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit a judgement
Other bias	Unclear risk	Conference abstract; insufficient information to permit a judgement. Funding mentioned (BTTB Centre).