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. 2020 Jan 25;2020(1):CD012501. doi: 10.1002/14651858.CD012501.pub2

Comparison 3. 0.10 mg.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 LDL‐cholesterol RCTs 7 1908 Mean Difference (IV, Fixed, 95% CI) ‐22.40 [‐23.71, ‐21.10]
2 Total cholesterol RCTs 6 1677 Mean Difference (IV, Fixed, 95% CI) ‐16.72 [‐17.76, ‐15.68]
3 HDL‐cholesterol RCTs 6 1675 Mean Difference (IV, Fixed, 95% CI) 4.49 [3.04, 5.94]
4 Triglycerides RCTs 4 731 Mean Difference (IV, Fixed, 95% CI) ‐16.17 [‐20.46, ‐11.89]
5 LDL‐cholesterol non‐RCTs 4 419 Mean Difference (Fixed, 95% CI) ‐23.84 [‐25.14, ‐22.54]
6 Total cholesterol non‐RCTs 4 437 Mean Difference (Fixed, 95% CI) ‐16.81 [‐17.74, ‐15.87]
7 HDL‐cholesterol non‐RCTs 4 437 Mean Difference (Fixed, 95% CI) 3.20 [1.85, 4.56]
8 Triglycerides non‐RCTs 4 426 Mean Difference (Fixed, 95% CI) ‐6.87 [‐10.18, ‐3.56]
9 WDAEs 4 942 Risk Ratio (M‐H, Fixed, 95% CI) 1.05 [0.40, 2.76]