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. 2020 Jan 25;2020(1):CD012501. doi: 10.1002/14651858.CD012501.pub2

Comparison 5. 0.20 mg.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 LDL‐cholesterol RCTs 7 2140 Mean Difference (IV, Fixed, 95% CI) ‐28.37 [‐29.66, ‐27.07]
2 Total cholesterol RCTs 6 1589 Mean Difference (IV, Fixed, 95% CI) ‐21.17 [‐22.24, ‐20.11]
3 HDL‐cholesterol RCTs 6 1584 Mean Difference (IV, Fixed, 95% CI) 4.69 [3.21, 6.18]
4 Triglycerides RCTs 5 780 Mean Difference (IV, Fixed, 95% CI) ‐16.21 [‐20.39, ‐12.02]
5 LDL‐cholesterol non‐RCTs 8 358 Mean Difference (Fixed, 95% CI) ‐26.65 [‐28.01, ‐25.29]
6 Total cholesterol non‐RCTs 8 364 Mean Difference (Fixed, 95% CI) ‐18.91 [‐19.86, ‐17.96]
7 HDL‐cholesterol non‐RCTs 7 349 Mean Difference (Fixed, 95% CI) 6.14 [4.71, 7.58]
8 Triglycerides non‐RCTs 6 328 Mean Difference (Fixed, 95% CI) ‐10.43 [‐13.70, ‐7.15]
9 WDAEs 4 1102 Risk Ratio (M‐H, Fixed, 95% CI) 0.86 [0.31, 2.37]