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. 2004 Jul 19;2004(3):CD003678. doi: 10.1002/14651858.CD003678.pub2

Summary of findings 2. Pre and post operative medical therapies versus placebo for endometriosis.

Pre and post operative medical therapies versus placebo for endometriosis
Patient or population: patients with infertility associated with endometriosis 
 Intervention: Post surgical medical therapies 
 Comparison: Pre and post‐surgical medical therapy with GnRHa
Outcomes Illustrative comparative risks* (95% CI) Relative effect 
 (95% CI) No of Participants 
 (studies) Quality of the evidence 
 (GRADE) Comments
Assumed risk Corresponding risk
Pre and post‐surgical medical therapy with GnRHa Post surgical medical therapies
Pregnancy Rate 500 per 1000 0 per 1000 
 (0 to 0) RR 0 
 (0 to 0) 25 
 (1 study) ⊕⊕⊝⊝ 
 low1  
*The basis for the assumed risk (e.g. the median control group risk across studies) is provided in footnotes. The corresponding risk (and its 95% confidence interval) is based on the assumed risk in the comparison group and the relative effect of the intervention (and its 95% CI). 
 CI: Confidence interval; RR: Risk ratio;
GRADE Working Group grades of evidence 
 High quality: Further research is very unlikely to change our confidence in the estimate of effect. 
 Moderate quality: Further research is likely to have an important impact on our confidence in the estimate of effect and may change the estimate. 
 Low quality: Further research is very likely to have an important impact on our confidence in the estimate of effect and is likely to change the estimate. 
 Very low quality: We are very uncertain about the estimate.

1 Description of randomisation , allocation concealment and blinding not adequate.