1. Descriptive data for trials not included in the meta‐analysis.
Study ID | Comparison | Outcome | n | Conclusion |
Donnez 1994 | pre‐surgical GNRHa (goserelin) versus no medical therapy | mean endometrioma size | 40/40 | favouring goserelin mean difference ‐1.81cm (95% CI ‐2.05 to 1.57) |
Shaw 2001 | pre‐surgical GNRHa (goserelin) versus no medical treatment | change in endometrioma size | 21/27 | favouring goserelin adj mean difference ‐1.25 cm (95% CI ‐2.42 to ‐0.08) |
Shaw 2001 | complete excision of cyst | 21/27 | no difference 13/21 (72%) and 16/27 (73%) had cysts completely excised at surgery |
|
Shaw 2001 | recurrence of residual cysts at 6 months | 21/27 | favours goserelin 2/21 (10%) and 4/27 (15%) had recurrence of residual cysts |
|
Shaw 2001 | mean rAFS scores | 21/27 | no difference 41.7, 42.5 (no SD given) |
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Telimaa 1987 | MPA versus placebo | pain | 17/8 | pain scores after 12 months assessed with 4 point scales; MPA 1.8; Placebo 4.4 "significant difference" |
Telimaa 1987 | danazol versus placebo | pain | 18/8 | pain scores after 12 months assessed with 4 point scales; danazol 2.5; placebo 4.4, "significant difference" |
Telimaa 1987 | MPA versus placebo | patient satisfaction | 17/8 | patient satisfaction achieved in MPA 84% vs placebo 24% |
Telimaa 1987 | danazol versus placebo | patient satisfaction | 18/8 | patient satisfaction achieved in danazol 84% vs placebo 24% |
Tsai 2004 | post‐surgical leuprolide/danazol versus no treatment | cumulative pregnancy rate at 12 months after clomiphene stimulation in both groups | 15/30 | no difference 56.7% and 54.5% |
Yang 2006 | post‐surgical gestrinone versus no medical treatment | disease recurrence at 6‐30 months | 19/13 | favours medical treatment 1/19 and 4/13 (p<0.05) |
Audebert 1998 | pre‐surgical versus post‐surgical GnRHa (nafarelin) | AFS scores | 25/28 | total AFS score after 6 months was 0 and 6 in pre and post groups respectively (p= 0.007); no SD or SE given and not calculable. |
Audebert 1998 | AFS scores | 25/28 | adhesion AFS score after 6 months was 0 and 2 in pre and post groups respectively (p= 0.007), no SD or SE given and not calculable. | |
Audebert 1998 | AFS scores | 25/28 | implant AFS score after 6 months was 0 and 4 in pre and post groups respectively (p= 0.05), no SD or SE given and not calculable. | |
Audebert 1998 | ease of surgery | 25/28 | surgery was easy in 56% of patients with GnRHa treatment pre‐surgery (Grp II) compared to 35.7% in the post‐surgery group (Grp I) |