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. 2004 Jul 19;2004(3):CD003678. doi: 10.1002/14651858.CD003678.pub2

Yang 2006.

Methods Location: Harbin, China 
 No. of centres: one
Recruitment period:March 2002 to March 2004
Participants Inclusion criteria: women with stage 3 endometriosis who had undergone conservative or semi‐conservative surgery, with normal renal function and blood count, aged 23 to 42 
 Exclusion criteria: history of hypertension, heart disease, diabetes mellitis, had undergone hormone therapy in 6 months prior to surgery 
 No. randomised: 52 
 No. analysed: unclear
Interventions Post‐operative 
 Gr A (n=20): yiweining (YWN) 200 ml orally twice daily, for 3 months, starting on 7th post‐operative day 
 Gr B (n=19): gestrinone 2.5 mg twice weekly, SC? for 3‐6 months, starting on 7th post‐operative day
Gr C (n=13): control ‐ no treatment
Outcomes Pregnancy, recurrence of endometriosis, adverse effects
Notes Power calculation: not stated 
 Funding: Fund of National Science of Heilongjiang Province
Email sent to corresponding author requesting additional information April 2010 ‐ mailbox not found
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk "randomly divided" ‐ no details of method of sequence generation given
Allocation concealment (selection bias) Unclear risk not mentioned
Blinding (performance bias and detection bias) 
 All outcomes High risk not mentioned, no placebo used
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk not clear how many of the randomised patients are included in the outcomes (% only given)
Selective reporting (reporting bias) Unclear risk pregnancy and recurrence reported ‐ no details as criteria for measuring these
Other bias Low risk groups are similar in age and type of surgery at baseline

NS = not stated 
 IM = intramuscular

SC = subcutaneous