3. Outcomes reported by studies of contact lens interventions^a.

Outcomes	Interventions studied
	Soft bifocal contact lenses: 4studies	Rigid gas permeable contact lenses: 2 studies	Orthokeratology: 3 studies	Spherical aberration soft contact lenses: 2 studies
Primary outcome: change in refractive error	Analysis 4.1	Analysis 5.1	No data for analysis	Data reported by both studies, but not meta‐analyzable
Secondary outcome: change in axial length	Analysis 4.2	Analysis 5.2	Analysis 6.1	Data reported by both studies, but not meta‐analyzable
Secondary outcome: change in corneal radius of curvature	Analysis 4.3	Analysis 5.3	No data for analysis	Not reported
Adverse effects	Six children in 1 study withdrew from the study, 3 from each group (CONTROL Study 2016)	Not reported	Adverse effects reported from all 3 studies	One study reported 1 child with allergic conjunctivitis and 1 with contact dermatitis

^aCompared with fully corrected single vision lenses or contact lenses.