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. 2020 Jan 20;2020(1):CD011628. doi: 10.1002/14651858.CD011628.pub2

Fairris 1984.

Methods Placebo‐controlled (double‐blind), parallel‐group trial
Number of centres not stated
Period of inclusion not stated
Participants Inclusion criteria
Not stated
Exclusion criteria
Not stated
Baseline data
Not stated (n = 6 participants)
Withdrawal: no dropouts
Interventions Intervention
A: superficial X‐ray therapy (N = 9 sites)
Control intervention
B: placebo (N = 9 sites)
Co‐interventions: none
Duration of treatment: 18 weeks
Outcomes No primary or secondary outcome pre‐specified
Grade of severity at each visit (no precision)
Participants were reviewed 6, 9, and 18 weeks after the start of X‐ray therapy. During each visit, patient and observer separately graded severity of the disease at both sites
Notes Available only as an abstract; hence, many details are missing and some are not clear
Funding: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Comment: no indication on randomisation sequence generation
Allocation concealment (selection bias) Unclear risk Comment: no indication on the process to guarantee allocation concealment
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Comment: the intervention is radiotherapy on the treated side and placebo on the other side
No indication of the measures used to guarantee blinding of participants and personnel
Blinding of outcome assessment (detection bias) 
 All outcomes Unclear risk Comment: the intervention is radiotherapy on the treated side and placebo on the other side. No indication of the measures used to guarantee blinding of outcome assessors
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Comment: no indication on dropout nor on eventual ITT analysis
Selective reporting (reporting bias) Unclear risk Comment: no protocol; no primary outcome specified