Fairris 1984.
Methods | Placebo‐controlled (double‐blind), parallel‐group trial Number of centres not stated Period of inclusion not stated |
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Participants |
Inclusion criteria Not stated Exclusion criteria Not stated Baseline data Not stated (n = 6 participants) Withdrawal: no dropouts |
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Interventions |
Intervention A: superficial X‐ray therapy (N = 9 sites) Control intervention B: placebo (N = 9 sites) Co‐interventions: none Duration of treatment: 18 weeks |
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Outcomes | No primary or secondary outcome pre‐specified Grade of severity at each visit (no precision) Participants were reviewed 6, 9, and 18 weeks after the start of X‐ray therapy. During each visit, patient and observer separately graded severity of the disease at both sites |
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Notes | Available only as an abstract; hence, many details are missing and some are not clear Funding: not reported |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Random sequence generation (selection bias) | Unclear risk | Comment: no indication on randomisation sequence generation |
Allocation concealment (selection bias) | Unclear risk | Comment: no indication on the process to guarantee allocation concealment |
Blinding of participants and personnel (performance bias) All outcomes | Unclear risk | Comment: the intervention is radiotherapy on the treated side and placebo on the other side No indication of the measures used to guarantee blinding of participants and personnel |
Blinding of outcome assessment (detection bias) All outcomes | Unclear risk | Comment: the intervention is radiotherapy on the treated side and placebo on the other side. No indication of the measures used to guarantee blinding of outcome assessors |
Incomplete outcome data (attrition bias) All outcomes | Unclear risk | Comment: no indication on dropout nor on eventual ITT analysis |
Selective reporting (reporting bias) | Unclear risk | Comment: no protocol; no primary outcome specified |