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. 2020 Jan 20;2020(1):CD011628. doi: 10.1002/14651858.CD011628.pub2

Lindelof 1990.

Methods Within‐patient, randomised trial
One centre in Stockholm
Period of inclusion not stated
Participants Inclusion criteria
Not stated
Exclusion criteria
  • Therapy during the 3 weeks preceding the trial


Baseline data: active treatment of lesions on 1 side of the body vs control on the other side (17 participants)
  • Median age (range), years: 54 (26 to 84)

  • Median duration of disease (range), years: 3 (0.5 to 35)

  • Proportion of participants with psoriatic lesions elsewhere: not specified


Withdrawal: 2 dropouts (1 because of flare‐up at other parts of the body, and 1 elderly participant because of illness)
Interventions Intervention 1
A: Grenz ray therapy (4 Gy) once per week
Intervention 2
B: placebo
Co‐interventions: none
Duration of treatment: 6 weeks
Outcomes No primary or secondary outcome pre‐specified
  • Improvement in score (based on a 5‐grade scale for erythema, itching, scaling, postulation, and distribution and on a visual analogue scale)

  • Adverse events

Notes Funding: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Quote: "The nurse treating the patient gave the active radiation or placebo treatment according to a randomised predetermined code"
Comment: no precision on how the code was generated
Allocation concealment (selection bias) Unclear risk Comment: no information on method to guarantee allocation concealment
Blinding of participants and personnel (performance bias) 
 All outcomes Low risk Quote: "double‐blind placebo‐controlled. Neither the patient nor the evaluating doctor knew which side had received active Grenz ray therapy"
Comment: probably done, but nurse treating the patient was not blind
Blinding of outcome assessment (detection bias) 
 All outcomes Low risk Quote: "double‐blind placebo‐controlled. Neither the patient nor the evaluating doctor knew which side had received active Grenz ray therapy"
Comment: probably done
Incomplete outcome data (attrition bias) 
 All outcomes Unclear risk Quote: "Of the 17 patients who started the trial, 2 patients failed to participate throughout the study"
Comment: no clear mention of how study authors deals with dropouts
Selective reporting (reporting bias) Unclear risk Comment: no protocol found to guarantee that all planned outcomes are presented in the results