Date | Event | Description |
---|---|---|
17 January 2018 | New search has been performed | The literature was searched in November 2017. Six new published trials and 16 new ongoing trials were identified. |
17 January 2018 | New citation required and conclusions have changed | Paracetamol has now been compared to placebo/no intervention and to indomethacin. Paracetamol appears more effective in closing a PDA than placebo/no intervention and has a similar effectiveness as ibuprofen or indomethacin with fewer side effects. Only one small study has reported on long‐term follow‐up. |