IRCT2016081729404N1.

Trial name or title	Safety and efficacy of venous paracetamol with venous ibuprofen in treatment of patent ductus arteriosus (PDA) among premature neonates hospitalised in NICU, Zanjan Ayatollah Musavi Hospital in 2016 to 2017
Methods	Randomised non‐blinded trial
Participants	Neonate ≤ 34 weeks with PDA diagnosis by echocardiography
Interventions	15 infants received paracetamol 15 mg/kg every 6 h for 3 days 15 infants received ibuprofen with a dose of 10 mg/kg in the first day and 5 mg/kg in the following second and third days
Outcomes	PDA size before and after treatment measured with echocardiography by paediatric cardiologist
Starting date	March 2017
Contact information	Dr. Abolfazl Ebadi, Musavi hospital , Gavazang, Zanjan, Iran
Notes	Recruitment complete