Comparison 5. Assisted vaginal birth (vacuum extraction or forceps) ‐ paracetamol suppositories vs placebo suppositories.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Modified facies scores (possible score 0 to 4) 0, 1 or 2 at 1, 7, 13 and 19 hours	1	119	Risk Ratio (M‐H, Fixed, 95% CI)	0.95 [0.75, 1.20]
2 Modified facies scores (possible score 0 to 4) 3 or 4 at 1, 7, 13 and 19 hours	1	119	Risk Ratio (M‐H, Fixed, 95% CI)	1.14 [0.66, 1.96]
3 EDIN score at 2 hours of age	1	123	Mean Difference (IV, Fixed, 95% CI)	1.0 [0.60, 1.40]
4 EDIN score at 4 hours of age	1	123	Mean Difference (IV, Fixed, 95% CI)	0.0 [‐0.22, 0.22]
5 Difference in acute BPSN pain scores before and after heel lance at 2 to 3 days of life (by nurses)	1	123	Mean Difference (IV, Fixed, 95% CI)	2.0 [1.56, 2.44]
6 Difference in acute BPSN pain scores before and after heel lance at 2 to 3 days of life (by video)	1	123	Mean Difference (IV, Fixed, 95% CI)	2.0 [1.47, 2.53]
7 Infants who cried following heel lance	1	123	Risk Difference (M‐H, Fixed, 95% CI)	0.15 [‐0.02, 0.33]
8 Time spent crying (seconds) after heel lance	1	123	Mean Difference (IV, Fixed, 95% CI)	19.0 [14.12, 23.88]