Table 2.
Clinical and Demographic Characteristics of Patients With and Without Klebsiella pneumoniae Colonization
| 2014 Cohort | 2016 Cohort | |||||
|---|---|---|---|---|---|---|
| Variable | No. | Kp-Colonized | P Value | No. | Kp-Colonized | P Value |
| Female | 591 | 116 (19.63) | .035 | 548 | 37 (6.75) | .494 |
| Male | 618 | 93 (15.05) | 695 | 54 (7.77) | ||
| Age | .024 | .254 | ||||
| <50 y | 347 | 42 (12.10) | 344 | 21 (6.10) | ||
| 51–60 y | 275 | 51 (18.55) | 249 | 14 (5.62) | ||
| 61–70 y | 306 | 59 (19.28) | 333 | 26 (7.81) | ||
| 71+ y | 281 | 57 (20.28) | 317 | 30 (9.46) | ||
| Race | .386 | .119 | ||||
| White | 990 | 169 (17.1) | 1059 | 71 (6.7) | ||
| Black | 128 | 27 (21.1) | 121 | 14 (11.5) | ||
| Other | 91 | 13 (14.2) | 63 | 6 (9.5) | ||
| Length of stay | .954 | .877 | ||||
| <4 d | 357 | 63 (17.65) | 333 | 22 (6.61) | ||
| 4–7 d | 267 | 48 (17.98) | 277 | 20 (7.22) | ||
| 7–14 d | 302 | 52 (17.22) | 267 | 19 (7.12) | ||
| 14+ d | 283 | 46 (16.25) | 366 | 30 (8.20) | ||
| Death in 30 d | 110 | 23 (20.91) | .292 | 120 | 15 (12.50) | .022 |
| No death in 30 d | 1099 | 186 (16.92) | 1123 | 76 (6.77) | ||
| Later K. pneumoniae clinical culture | 47 | 23 (48.9) | <.0001 | 24 | 5 (20.8) | .0263 |
| No later K. pneumoniae clinical culture | 1162 | 186 (16.0) | 1219 | 86 (7.1) | ||
| Later K. pneumoniae infection | 25 | 13 (52.0) | <.0001 | 11 | 2 (18.1) | .1897 |
| No later K. pneumoniae infection | 1184 | 196 (16.6) | 1232 | 89 (7.2) | ||
| VRE-colonized | 96 | 23 (23.96) | .072 | 118 | 16 (13.56) | .006 |
| Not VRE-colonized | 1113 | 186 (16.71) | 1125 | 75 (6.67) | ||
| Neurologic disorder | 95 | 16 (16.84) | >.999 | 65 | 11 (16.92) | .005 |
| No neurologic disorder | 1114 | 193 (17.32) | 1178 | 80 (6.79) | ||
| Congestive heart failure | 127 | 25 (19.69) | .457 | 123 | 14 (11.38) | .097 |
| No congestive heart failure | 1082 | 184 (17.01) | 1120 | 77 (6.88) | ||
| Pulmonary circulation disorder | 72 | 13 (18.06) | .872 | 67 | 10 (14.93) | .026 |
| No pulmonary circulation disorder | 1137 | 196 (17.24) | 1176 | 81 (6.89) | ||
| Peripheral vascular disease | 90 | 20 (22.22) | .194 | 99 | 7 (7.07) | >.999 |
| No peripheral vascular disease | 1119 | 189 (16.89) | 1144 | 84 (7.34) | ||
| Hypertension | 449 | 92 (20.49) | .027 | 198 | 10 (5.05) | .233 |
| No hypertension | 760 | 117 (15.40) | 1045 | 81 (7.75) | ||
| Admitted overnight 180 d prior | 701 | 124 (17.69) | .664 | 676 | 55 (8.14) | .907 |
| Not admitted overnight 180 d prior | 508 | 85 (16.73) | 567 | 36 (6.35) | ||
| Antibiotic exposure | 110 | 12 (10.91) | .064 | 170 | 10 (5.88) | .438 |
| No antibiotic exposure | 1099 | 197 (17.93) | 1073 | 81 (7.55) | ||
| Central line | 92 | 12 (13.04) | .263 | 147 | 7 (4.76) | .205 |
| No central line | 1117 | 197 (17.93) | 1096 | 84 (7.66) | ||
| Urinary catheter | 87 | 17 (19.54) | .564 | 136 | 5 (3.68) | .084 |
| No urinary catheter | 1122 | 192 (17.11) | 1107 | 86 (7.77) | ||
| Hemoglobin baseline | .204 | .554 | ||||
| <9.9 | 313 | 58 (18.53) | 319 | 29 (9.09) | ||
| 10–11.7 | 303 | 58 (19.14) | 316 | 22 (6.96) | ||
| 11.8–13.4 | 303 | 55 (18.15) | 303 | 19 (6.27) | ||
| 13.5+ | 288 | 38 (13.19) | 303 | 21 (6.93) | ||
Differences between colonized and not-colonized patients were calculated using the Student t test for continuous variables and the chi-square or Fisher exact test for categorical variables.
Abbreviations: Kp, Klebsiella pneumoniae; VRE, vancomycin-resistant Enterococci.