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. 2018 Aug 16;14(12):2104–2116. doi: 10.1080/15548627.2018.1504716

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Figure 6. — A model of the function of ATG101 in the ULK1 complex. The interaction between ATG13^HORMA and ATG14 is indicated with the magenta curved arrow and the ULK1 kinase phosphorylates several components of PtdIns3K complex indicated by the cyan curved arrow. The C-terminal region of ATG101 (green ribbon) that binds to PtdIns3K complexes (C1 and C2) and is indicated by the blue dotted oval. A WF finger of ATG101 (red dotted oval) cannot interact with the PtdIns3K complex but affects WIPI1 or ZFYVE1 function indicated by the purple arrow. KD, kinase domain; MIT, microtubule interacting and transport; MIM, MIT-interacting motif; RB1CC1, RB1 inducible coiled-coil 1; WIPI1, WD repeat domain, phosphoinositide interacting 1; ZFYVE1, zinc finger FYVE-type containing 1.