Table 1. Statistics split by sex for behavioral experiments in Figure 2.
| Sex | Genotype (N) | Mean (SEM) | Statistics |
|---|---|---|---|
| Rotarod – learning rate (rpm/trial; trial 3- trial 1) | |||
| Male | Control (28) | 57.29 (10.17) | p = 0.0088 |
| dSPNAtg7cKO (20) | 15.85 (8.333) | ||
| iSPNAtg7cKO (11) | 22.45 (13.17) | ||
| Female | Control (22) | 57.18 (12.89) | p = 0.0029 |
| dSPNAtg7cKO (14) | 38.43 (12.69) | ||
| iSPNAtg7cKO (12) | −11.92 (12.33) | ||
| Combined | Control (50) | 57.24 (7.954) | p = 0.0001 |
| dSPNAtg7cKO (34) | 25.15 (7.306) | ||
| iSPNAtg7cKO (23) | 4.522 (9.526) | ||
| Sex x Genotype F(2,101) = 2.218 p = 0.1141 | |||
| Weight (g) | |||
| Male | Control (31) | 26.07 (0.4074) | p = 0.0003 |
| dSPNAtg7cKO (19) | 22.66 (0.8216) | ||
| iSPNAtg7cKO (12) | 24.67 (0.6438) | ||
| Female | Control (31) | 21.15 (0.4341) | p = 0.0003 |
| dSPNAtg7cKO (11) | 17.85 (0.5850) | ||
| iSPNAtg7cKO (13) | 20.29 (0.4439) | ||
| Sex x Genotype F(2,111) = 0.1073 p = 0.8983 | |||
| Open Field – Distance traveled (cm) | |||
| Male | Control (17) | 6777 (397.9) | p = 0.0159 |
| dSPNAtg7cKO (7) | 8073 (883.5) | ||
| iSPNAtg7cKO (6) | 9318 (573.1) | ||
| Female | Control (15) | 9307 (369.4) | p = 0.0257 |
| dSPNAtg7cKO (7) | 7967 (773.3) | ||
| iSPNAtg7cKO (8) | 10433 (584.5) | ||
| Combined | Control (32) | 7963 (351.7) | p = 0.0048 |
| dSPNAtg7cKO (15) | 7762 (585.4) | ||
| iSPNAtg7cKO (15) | 9955 (427.4) | ||
| Sex x Genotype F(2,54) = 3.045 p = 0.0558 | |||
| Open Field – Stereotypies (data normalized) | |||
| Male | iSPNCtrl (7) | 1.00 (0.030) | p = 0.0293 |
| iSPNcKO (6) | 1.136 (0.047) | ||
| Female | iSPNCtrl (8) | 1.00 (0.038) | p = 0.0819 |
| iSPNcKO (8) | 1.094 (0.032) | ||
| Combined | iSPNCtrl (15) | 1.00 (0.024) | p = 0.0043 |
| iSPNcKO (14) | 1.112 (0.027) | ||
| Sex x genotype F(1,25) = 0.3226 p = 0.5751 | |||
| Grooming bouts | |||
| Male | iSPNCtrl (11) | 3.091 (0.8252) | p = 0.0542 |
| iSPNcKO (13) | 5.846 (1.031) | ||
| Female | iSPNCtrl (12) | 3.500 (0.4174) | p = 0.0048 |
| iSPNcKO (13) | 7.385 (1.130) | ||
| Combined | iSPNCtrl (23) | 3.304 (0.4420) | p = 0.0007 |
| iSPNcKO (26) | 6.615 (0.7648) | ||
Sex x genotype F(1,45) = 0.3781 p = 0.5417.