Table 2. Cox Regression Analysis for Liver Event in the Derivation Cohort.
| Univariate Analyses |
Multivariate Analyses |
|||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P Value | HR | 95% CI | P Value | |
| Albumin ratio | 0.007 | 0.002-0.020 | <0.001 | 0.052 | 0.013-0.211 | <0.001 |
| Platelet ratio | 0.336 | 0.247-0.457 | <0.001 | 0.362 | 0.255-0.514 | <0.001 |
| BIL12 ratio | 1.476 | 1.394-1.563 | <0.001 | 1.427 | 1.317-1.210 | <0.001 |
| TA12 ratio | 1.225 | 1.180-1.271 | <0.001 | 1.150 | 1.093-1.210 | <0.001 |
| ALP12 ratio | 1.275 | 1.216-1.337 | <0.001 | 1.103 | 1.030-1.183 | 0.005 |
| Na ratio | 0.001 | 0.001-0.002 | <0.001 | — | — | — |
| Creatinine ratio | 0.385 | 0.131-1.129 | 0.082 | — | — | — |
| BIL ratio | 1.178 | 1.148-1.208 | <0.001 | — | — | — |
| ALP ratio | 1.044 | 1.027-1.061 | <0.001 | — | — | — |
| TA ratio | 1.019 | 0.999-1.039 | 0.050 | — | — | — |
| INR | 1.420 | 0.839-2.401 | 0.191 | — | — | — |
| IgG ratio | 2.430 | 1.676-3.523 | <0.001 | — | — | — |
| Age, years | 0.970 | 0.955-0.984 | <0.001 | — | — | — |
| Year of diagnosis | 0.941 | 0.919-0.964 | <0.001 | — | — | — |
| Female | 0.816 | 0.443-1.503 | 0.514 | — | — | — |
| ANA+ | 1.423 | 0.937-2.1 | 0.048 | — | — | — |
| AMA+ | 1.090 | 0.589-2.020 | 0.782 | — | — | — |
| SMA+ | 1.114 | 0.563-2.020 | 0.756 | — | — | — |
| Splenomegaly | 8.453 | 5.969-11.971 | <0.001 | — | — | — |
| Ascites | 11.732 | 6.283-21.905 | <0.001 | — | — | — |
Splenomegaly refers to a spleen length >12 cm.
Abbreviations: AMA, anti-mitochondrial antibodies; ANA, anti-nuclear antibodies; ALP, alkaline phosphatase; ALP12, alkaline phosphatase after 12 months of UDCA; BIL12, bilirubin after 12 months of UDCA; CI, confidence interval; HR, hazard ratio; IgG, immunoglobulin G; INR, international normalized ratio; n, number; SMA, anti-smooth muscle antibodies; TA12, transaminases after 12 months of UDCA.