Table 3:
Statistically significant OTUs by taxonomy using Kruskal-Wallis testing comparing cases (all patients with CAD) versus controls (all patients without CAD). The false discovery rate (FDR) of the set is 0.67. FDR is the expected proportion of type 1 errors when conducting multiple comparisons.
| OTU count | P-value | Taxonomy† | |
|---|---|---|---|
| Case (mean) | Control (mean) | ||
| 195.69 | 3.91 | 0.0008 | p__Actinobacteria; c__Actinobacteria; o__Actinomycetales; f__Corynebacteriaceae; g__Corynebacterium; s__ |
| 122.51 | 2.34 | 0.0087 | p__Actinobacteria; c__Actinobacteria; o__Actinomycetales; f__Nocardiaceae; g__Rhodococcus; s__ |
| 0.00 | 1.13 | 0.0078 | p__Actinobacteria; c__Coriobacteriia; o__Coriobacteriales; f__Coriobacteriaceae; g__Adlercreutzia; s__ |
| 0.00 | 0.50 | 0.0018 | p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Bacteroidaceae; g__Bacteroides; s__ |
| 5.57 | 0.16 | 0.0026 | p__Bacteroidetes; c__Bacteroidia; o__Bacteroidales; f__Porphyromonadaceae; g__Parabacteroides; s__ |
| 12.71 | 12.13 | 0.0014 | p__Firmicutes; c__Bacilli; o__Bacillales; f__Staphylococcaceae; g__Staphylococcus; s__ |
| 3.69 | 3.19 | 0.0086 | p__Firmicutes; c__Bacilli; o__Bacillales; f__Staphylococcaceae; g__Staphylococcus; s__ |
| 368.89 | 307.47 | 0.0028 | p__Firmicutes; c__Bacilli; o__Bacillales; f__Staphylococcaceae; g__Staphylococcus; s__aureus |
| 5.63 | 6.69 | 0.0063 | p__Firmicutes; c__Bacilli; o__Bacillales; f__Planococcaceae; g__; s__ |
| 30.34 | 23.88 | 0.0083 | p__Firmicutes; c__Bacilli; o__Bacillales; f__Planococcaceae; g__; s__ |
| 141.54 | 74.94 | 0.0029 | p__Firmicutes; c__Bacilli; o__Lactobacillales; f__Aerococcaceae; g__Facklamia; s__ |
| 0.00 | 2.16 | 0.0037 | p__Firmicutes; c__Bacilli; o__Lactobacillales; f__Lactobacillaceae; g__Lactobacillus; s__ |
| 1.69 | 0.06 | 0.0039 | p__Firmicutes; c__Bacilli; o__Lactobacillales; f__Streptococcaceae; g__Streptococcus; s__ |
| 5.80 | 0.31 | 0.0091 | p__Firmicutes; c__Bacilli; o__Lactobacillales; f__Streptococcaceae; g__Streptococcus; s__ |
| 32.60 | 2.41 | 0.0052 | p__Firmicutes; c__Bacilli; o__Lactobacillales; f__Streptococcaceae; g__Streptococcus; s__ |
| 0.03 | 2.81 | 0.0032 | p__Firmicutes; c__Clostridia; o__Clostridiales; f__Lachnospiraceae; g__; s__ |
| 0.00 | 5.06 | 0.0078 | p__Firmicutes; c__Clostridia; o__Clostridiales; f__Lachnospiraceae; g__; s__ |
| 0.00 | 4.69 | 0.0078 | p__Firmicutes; c__Clostridia; o__Clostridiales; f__Lachnospiraceae; g__Dorea; s__ |
| 0.00 | 0.34 | 0.0078 | p__Firmicutes; c__Clostridia; o__Clostridiales; f__Lachnospiraceae; g__Ruminococcus; s__ |
| 0.54 | 1.91 | 0.0104 | p__Firmicutes; c__Clostridia; o__Clostridiales; f__Tissierellacea; g__Helcococcus; s__ |
| 0.11 | 7.75 | 0.0046 | p__Fusobacteria; c__Fusobacteriia; o__Fusobacteriales; f__Fusobacteriaceae; g__Fusobacterium; s__ |
†
Taxonomy nomenclature: p = phylum, c = class, o = order, f = family, g = genus, s = species. All denoted OTUs are within kingdom Bacteria. The narrow taxonomic rank in each significant OTU is in bolded text.