TABLE 3.
Perioperative Data and Outcomes of Resected Locally Advanced Pancreatic Cancer Patients
| Variable | Resected Patients (n = 84) |
|---|---|
| Type of operation, n (%) | |
| Whipple | 44 (53%) |
| DP-CAR | 23 (27%) |
| Distal pancreatectomy | 16 (19%) |
| Total pancreatectomy | 1 (1%) |
| Length of hospital stay, days | |
| Median (IQR) | 8 (6–11) |
| Morbidity, n (%) | |
| ≤ Clavien-Dindo grade IIIa | 45 (54%) |
| ≥ Clavien-Dindo grade IIIb | 4 (5%) |
| Thirty-day readmission, n (%) | 24 (29%) |
| Thirty-day mortality, n (%) | 1 (1%) |
| Ninety-day mortality, n (%) | 3 (4%) |
| Adjuvant chemotherapy, n (%) | 25 (30%) |
| Months of adjuvant chemotherapy administered | |
| Median (IQR) | 3 (2–4) |
| Disease recurrence, n (%) | 40 (48%) |
| Recurrence site, n (%) | |
| Local | 13 (33%) |
| Liver | 9 (23%) |
| Carcinomatosis | 7 (18%) |
| Multiple sites | 7 (18%) |
| Lung | 4 (10%) |
| Tumor size in pathology report, mm | |
| Mean (SD) | 20 (16) |
| Tumor differentiation, n (%) | |
| Well | 2 (2%) |
| Moderate | 45 (54%) |
| Poor | 16 (19%) |
| Unknown | 19 (23%) |
| Resection margin status | |
| Negative (R0, >1 mm), n (%) | 75 (89%) |
| Positive (R1, ≤1 mm), n (%) | 9 (11%) |
| Positive lymph nodes, n (%) | 21 (25%) |
| Perineural invasion, n (%) | 48 (57%) |
| Perivascular invasion, n (%) | 18 (21%) |
| Treatment response, n (%) | |
| Complete (grade 0) | 5 (6%) |
| Extensive (grade 1) | 27 (32%) |
| Moderate (grade 2) | 33 (39%) |
| Poor (grade 3) | 13 (16%) |
| Unknown | 6 (7%) |
DP-CAR indicates distal pancreatectomy with en bloc celiac artery resection (modified Appleby procedure); IQR, interquartile range; SBRT, stereotactic body radiation therapy; SD, standard deviation.