Table 3.

Metric comparison between manual (plan 1) and final CAP (plan 4)

Metric	Estimate (plan 1–plan 4 difference)	95% confidence interval	p value
Length (mm)	0.54	(− 2.94, 4.02)	0.762
Drilling angle (deg.)	1.11	(− 1.88, 4.10)	0.467
GM sampling ratio	−0.02	(− 0.05, 0.00)	0.098
Risk score	0.05	(0.02, 0.08)	0.003
Minimum distance from critical structure (mm)	−0.22	(− 0.43, − 0.01)	0.040

Estimates for differences between plan 1 and plan 4, for each metric, together with associated 95% confidence intervals and p values for a test of the null hypothesis that the true difference = 0. The estimates have been obtained from mixed-effects regression models that include within-patients random effects to account for within-patient clustering of electrodes