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. 2020 Jan 8;146(2):329–342. doi: 10.1007/s00432-019-03115-7

Fig.5.

Fig.5

YARS activated PI3K-Akt signaling in gastric cancer. For HGC-27/AGS cells, changes of the PI3K-Akt pathway representative members (p-S6, S6, p-Akt, Akt, p-Erk, Erk, p-mTOR, mTOR) and YARS after a YARS depletion or b YARS overexpression were assessed by western blot. c After YARS depletion in GC cells, 48 h responses to the concentration cascades of the PI3K-Akt pathway inhibitor BEZ235 were assessed with CCK-8 assay. v vector, Y YARS. *p < 0.05