FIGURE 7.

Motor-evoked potentials in the forelimb muscles. (A,B) Representative EMG responses in the triceps muscle in the wild-type (A) and DKO mice (B). Responses of EMGs in bilateral triceps muscles to four square-pulses of current stimulations (200-μs duration, 3-ms intervals, every 550 ms, 50–100 μA) to the M1 cortex were recorded. The EMGs were rectified and averaged 500 times. M1 stimulation on one side evoked motor potentials only in the contralateral triceps muscles in the wild-type mice, whereas the same stimulation evoked bilateral responses in the Sulf1/2 DKO mice. The asterisks indicate stimulation artifacts.