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. 2020 Jan 27;10:1191. doi: 10.1038/s41598-020-58256-4

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Cytochrome c oxidase activity in C. albicans cells, after exposed to varying concentrations of ETC-5, ETC-6 and ETC-7 for 3 h, exhibited significant decrease in enzyme activity in contrast to untreated control. Cells exposed to 250 μmol/l H₂O₂ were used as negative and positive controls, respectively. Data are presented from three independent experiments using means ± S.D. ****P < 0.0001, ***P: 0.0001. *P: 0.0104.