Table 2.
Top 10 of the greatest genes expression changes in SH4 with vs without GM2/GD2.
| Symbol | Gene name | Expr Fold change | p-value |
|---|---|---|---|
| Up-regulation | |||
| PTPRD | Protein tyrosine phosphatase receptor type D | 735.0563 | 0.005722 |
| B4GALNT1 | Beta-1,4-N-acetyl- galactosaminyltransferase 1 | 359.3801 | 1.4E-150 |
| POSTN | Periostin | 286.3453 | 4.95E-26 |
| SERPINB2 | Serpin family B member 2 | 240.9988 | 7.94E-06 |
| HLA-DRB1 | human leukocyte antigen, class II, DR beta 1 | 228.4819 | 1.07E-05 |
| IL13RA2 | Interleukin 13 receptor alpha 2 | 191.2431 | 0.000616 |
| CSMD1 | CUB and sushi multiple domains 1 | 188.313 | 7.75E-05 |
| MYBPC1 | Myosin binding protein C type 1 | 182.0119 | 0.000805 |
| ADGRL2 | Adhesion G protein- coupled receptor L2 | 158.3556 | 4.73E-92 |
| TNFRSF14 | TNF receptor superfamily member 14 | 142.9792 | 0.011144 |
| Down-regulation | |||
| CPVL | Carboxypeptidase vitellogenic like | −1370.3 | 3.27E-37 |
| MAGEA12 | Melanoma-associated antigen 12 | −1143.23 | 9.84E-16 |
| CSAG1 | Chondrosarcoma associated gene 1 | −676.619 | 8.41E-12 |
| GIPC3 | PDZ domain containing family Member 3 | −535.495 | 1.85E-20 |
| CPM | Carboxypeptidase M | −484.607 | 3.42E-15 |
| ZXDA | Zinc finger, X-linked, duplicated A | −457.61 | 9.68E-09 |
| FAM83H | Family with sequence similarity 83 | −412.334 | 1.45E-08 |
| PRAME | Preferentially expressed antigen in melanoma | −411.078 | 0.000851 |
| GABRQ | Gamma-aminobutyric acid type A receptor theta subunit | −402.747 | 1.57E-21 |
| LDB2 | LIM domain binding 2 | −371.463 | 0.000011 |